The antifungal polyene macrolide antibiotic with a broad spectrum of action. It has a fungicidal effect. Natamycin sterols binds cell membranes, disturbing its integrity and function, which leads to the death of microorganisms. For natamycin sensitivity of most pathogenic yeasts, especially. Less sensitive to natamycin dermatophytes. Natamycin resistance in clinical practice does not occur. Natamycin tablets, thanks to enteric coating, is valid only in the intestine. Natamycin winstrol dosage is not absorbed from the gastrointestinal tract, through the intact skin and mucous membranes.
fungal diseases of the skin and mucous membranes caused by the pathogens susceptible to the drug, in Vol. H .:
- Acute pseudomembranous and acute atrophic candidiasis in patients with cachexia, immune deficiency, and after antibiotic therapy, corticosteroids, cytotoxic drugs;
- otomycosis, otitis externa, or primarily caused by fungi, or is complicated by candidiasis;
- candidiasis of the skin and nails;
- intestinal candidiasis;
- vaginitis, vulvitis, vulvovaginitis, balanoposthitis caused mainly fungi Candida;
Hypersensitivity to the drug.
Dosage and administration.
If intestinal candidiasis adults appoint 1 tab. 4 times / day. for an average of 1 week. Children appoint 1 tab. 2 times / day. When dermatomikozoh (in t. H. Skin candidiasis and nails, diaper rash in children) cream is applied to the affected surface of the skin and nails one or more times per day. In otomycosis skin surface smeared with cream 1 or more times a day.Before use, clean the ear of the drug. After the drug is placed in the ear canal turunda of natural material (cotton, wool).
When vaginitis, vulvitis, vulvovaginitis appoint 1 vaginal suppository for 3-6 days. Suppository inserted into the vagina in the supine position, as far as possible, 1 times / day. overnight. When thrust during vaginitis caused by Candida albicans, additionally prescribe tablets orally (1 tablet. 4 times / day. For 10-20 days) for the renovation of the hearth of Candida infection in the intestines. For the treatment of vulvovaginal lesions genitals partner winstrol dosage used in the form of a cream.
When balanoposthitis cream applied to the affected skin once or several times a day. The duration of treatment is determined individually. After the disappearance of the symptoms it is recommended to continue treatment for several days.
Interaction with other drugs
drug interactions Pimafucin preparation is not described.
Special instructions. Suppositories vaginal under the influence of body temperature quickly dissolved, forming a foamy mass, which contributes to uniform distribution of the active substance. In the case of chronic recurrent infections or topical treatment can be completed appointment tablets and cream. Ethanol, which is part of a vaginal suppository may cause hypersensitivity reactions. During menstruation suppositories therapy is interrupted. During treatment suppositories no need to exclude sex. However, it is recommended to conduct a survey of sexual partners and, in the case of vulvovaginal lesions, hold treatment pimafutsin. You should also provide for the use in treatment of barrier winstrol dosage contraceptives.
Pregnancy and lactation. Can be used pimafutsin during pregnancy and lactation.
On the part of the digestive tract: nausea and diarrhea (occurring during the first few days of taking the pills and going on their own in the course of treatment). Local reactions: possible mild irritation, burning sensation (when applying creams, vaginal suppositories).