Permikson has complex effects on the pathogenesis and symptoms of benign prostatic hyperplasia, due to the complementary effects of compound ingredients of the plant extract. Permikson has anti-androgenic, anti-inflammatory, winstrol before and after decongestant and anti-proliferative effects manifested selectively to prostate level. Thus the preparation has no effect on the levels of sex hormones in the blood without causing deterioration of sexual function, libido, potency, and does not alter the serum PSA (prostate-specific antigen).
Local Permiksona antiandrogenic effect associated steroids online for sale with inhibition of the enzyme 5-alpha reductase type I and II, is responsible for the conversion of testosterone in the prostate gland in its active form – dihydrotestosterone, and reduced binding to specific receptors on the latter. Reducing the formation of DHT leads to a decrease in the further growth of prostate volume.
The local anti-inflammatory effect is due to the influence of saw palmetto extract lipidosterolovogo creeping on the main mediators of cellular inflammation – inhibits the activity of phospholipase A2, cyclooxygenase and lipoxygenase. Permikson during the first weeks of treatment reduces capillary permeability and vascular stasis, reduces swelling and inflammation of the prostate, eliminates compression of the neck of the bladder and urinary canal, like alpha-blockers improves urodynamic indices. Local anti-proliferative effect of the drug is decreased activity of growth factors (especially the epidermal and fibroblast) and accelerated apoptosis in prostate cell processes, which is reflected in the inhibition of growth and consequent reduction in prostate volume. These properties contribute to the preparation, on the one hand, a decrease in pathological symptoms of benign prostatic hyperplasia (dysuria, pollakiuria, nocturia, pain and feelings of winstrol before and after stress during urination, incomplete emptying of the bladder), an increase in the volume and force of urination. On the other hand, it contributes Permikson further growth and inhibition of prostate volume.
Benign prostatic hyperplasia (BPH) prostate stage I and II.
: Hypersensitivity to the drug.
Dosing and Administration
Inside of 160 mg (2 tablets or 1 capsule) 2 times a day or once in the morning, not liquid, during a meal. The duration of treatment should be at least 3 months.
The optimum scheme and repeated courses of treatment prescribed by the physician sets and individually in each case on the basis of a diagnostic test.
In some cases, winstrol before and after may cause nausea, heartburn, gastralgia, usually passing while taking the drug with food. In rare cases – allergic reactions.